CHIEFLY CLINICAL.

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sort of regard to the periodical type of her organization. It never appeared that she studied excessively in other respects, or that her system was weakened while in college by fevers or other sickness. Not a great while after graduation, she began to show signs of failure, and some years later died under the writers care. A post-mortem ex animation was made, which disclosed no dis ease in any part of the body, except in the brain, where the microscope revealed com­mencing degeneration.

This was called an instance of death from over-work. Like the preceding case, it was not so much the result of over-work as of un-physiological work. She was unable to make a good brain, that could stand the wear and tear of life, and a good reproduc­tive system that should serve the race, at the same time that she was continuously spending her force in intellectual labor. Nature asked for a periodical remission,

and did not get it. And so Miss G-

died, not because she had mastered the